HIV Medicine

Lamivir Tablets

Approx Price: Rs 110 / Strip 
Minimum Order Quantity: 1 Strip
We are counted among the leading manufacturer, trader, exporter and supplier of best quality Lamivir Tablets that is widely used for the treatment of chronic hepatitis B. Owing to its effectiveness; our offered tablets are highly demanded in the market. At our premises, our offered tablets are processed using quality assured chemical compounds that are sourced from the reliable vendors of the market. Additionally, these tablets can get by our clients from us at reasonable prices.

Features:

  • Accurate composition
  • Highly effective
  • No side effect

Viraday (Tenofovir, Emtricitabine, Efavirenz) Tablets

Tenofovir and Lamivudine Tablets

Tenofovir and Lamivudine Tablets

Empetus (Ritonavir)

Approx Price: Rs 970 / Bottle 
Minimum Order Quantity: 1 Bottle
  • Item Code: 83994873
  • Empetus (Ritonavir)
  • Brand name: Empetus
  • Active Ingeridents(Generic Name) : Ritonavir
  • Company Name: Emcure
  • Package:30 Tablets/Bottle
  • Strength : 100mg

Indication:

Empetus (Ritonavir) is an antiretroviral medication used along with other medications to treat HIV/AIDS This combination treatment is known as highly active antiretroviral therapy . Often a low dose is used with other protease inhibitors. It may also be used in combination with other medications for hepatitis C.

Mechanism of action:

Empetus (Ritonavir) was originally developed as an inhibitor of HIV protease. It is one of the most complex inhibitors. It is now rarely used for its own antiviral activity, but remains widely used as a booster of other protease inhibitors. More specifically, Empetus (Ritonavir) is used to inhibit a particular liver enzyme that normally metabolizes protease inhibitors, cytochrome P450-3A4 (CYP3A4). The drug's molecular structure inhibits CYP3A4, so a low dose can be used to enhance other protease inhibitors. This discovery, which has drastically reduced the adverse effects and improved the efficacy of protease inhibitors and HAART, was first communicated in an article published in the journal AIDS in 1997 by researchers at the University of Liverpool. This effect does come with a price: it also affects the efficacy of numerous other medications, making it difficult to know how to administer them concurrently.

Dosage and Administration:

Use Empetus (Ritonavir) as directed by your doctor. Check the label on the medicine for exact dosing instructions.

 

· Take Empetus (Ritonavir) by mouth with meals.

· Swallow Empetus (Ritonavir) whole. Do not break, crush, or chew before swallowing.

· Continue to take Empetus (Ritonavir) even if you feel well. Do not miss any doses.

Side effects:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Abnormal skin sensations, especially around the mouth, fingers, and toes; diarrhea; headache; loss of appetite; mild stomach pain; nausea; taste changes; tiredness; vomiting; weakness.

Precaution:

Before taking Empetus (Ritonavir), tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

 

Before using this medication, tell your doctor or pharmacist your medical history, especially of: diabetes, heart problems (coronary artery disease, heart attack), hemophilia, high cholesterol/triglycerides, gout/high uric acid in the blood, liver problems (such as hepatitis B, hepatitis C), pancreatitis

 

Store:

Store Empetus (Ritonavir) in the original container at room temperature up to 86 degrees F (30 degrees C). If stored outside of the original container, throw away any part not used after 2 weeks. Storage at temperatures up to 122 degrees F (50 degrees C) is permitted for up to 7 days. Store away from heat, moisture, and light.

Emletra (Lopinavir /Ritonavir) Medicines

Approx Price: Rs 2,500 / Bottle 
Minimum Order Quantity: 1 Bottle
Item Code: 85672320

Emletra (Lopinavir /Ritonavir)

Brand name: Emletra

Active Ingeridents(Generic Name) : Lopinavir / Ritonavir

Company Name: Emcure

Package : 60 tablets

Strength : Lopinavir 200mg+ Ritonavir 50mg

Indication:

Treating HIV infection. It is used along with other medicines for HIV. Emletra (Lopinavir /Ritonavir) is a combination of 2 HIV protease inhibitors. It works by stopping the HIV virus from multiplying.

 

Mechanism of action:

Lopinavir:

Lopinavir inhibits the HIV viral protease enzyme. This prevents cleavage of the gag-pol polyprotein and, therefore, improper viral assembly results. This subsequently results in non-infectious, immature viral particles

Ritonavir :

Ritonavir inhibits the HIV viral proteinase enzyme which prevents cleavage of the gag-pol polyprotein, resulting in noninfectious, immature viral particles.

Dosage and Administration:

Use Emletra (Lopinavir /Ritonavir) as directed by your doctor. Check the label on the medicine for exact dosing instructions.

· Emletra (Lopinavir /Ritonavir) comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get Emletra (Lopinavir /Ritonavir) refilled.

· Take Emletra (Lopinavir /Ritonavir) by mouth with or without food.

· Swallow Emletra (Lopinavir /Ritonavir) whole. Do not break, crush, or chew before swallowing.

· Emletra (Lopinavir /Ritonavir) must be taken with other HIV medicines to be effective.

· If you are also taking didanosine, you may take it at the same time as Emletra (Lopinavir /Ritonavir) without food.

· Taking Emletra (Lopinavir /Ritonavir) at the same time each day will help you remember to take it.

Ask your health care provider any questions you may have about how to use Emletra (Lopinavir /Ritonavir).

Side effects:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Back pain; diarrhea; headache; muscle or joint pain; nausea; stomach pain; tiredness; vomiting; weakness.

Precaution:

Before taking this product, tell your doctor or pharmacist if you are allergic to either lopinavir or ritonavir; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details

 

Store:

Store Emletra (Lopinavir /Ritonavir) at room temperature, between 59 and 86 degrees F (15 and 30 degrees C) in a tightly closed container. Store away from heat, moisture, and light.

Efavir (Efavirenz) Medicines

Approx Price: Rs 1,890 / Bottle 
Minimum Order Quantity: 1 Bottle
Item Code: 83994383

Efavir (Efavirenz)

Brand name: Efavir

Active Ingeridents(Generic Name) : Efavirenz

Company Name: Cipla

Package: 30 Tablets/Bottle

Strength : 600mg

Indication:

This drug is used with other HIV medications to help control HIV infection. It helps to decrease the amount of HIV in your body so your immune system can work better. This lowers your chance of getting HIV complications (such as new infections, cancer) and improves your quality of life. Efavir (Efavirenz) belongs to a class of drugs known as non-nucleoside reverse transcriptase inhibitors (NNRTIs).

Mechanism of action:

Efavir (Efavirenz) falls in the NNRTI class of antiretrovirals. Both nucleoside and non-nucleoside RTIs inhibit the same target, the reverse transcriptase enzyme, an essential viral enzyme which transcribes viral RNA into DNA. Unlike nucleoside RTIs, which bind at the enzyme's active site, NNRTIs act allosterically by binding to a distinct site away from the active site known as the NNRTI pocket.

Efavir (Efavirenz) is not effective against HIV-2, as the pocket of the HIV-2 reverse transcriptase has a different structure, which confers intrinsic resistance to the NNRTI class.

Dosage and Administration:

Use Efavir (Efavirenz) as directed by your doctor. Check the label on the medicine for exact dosing instructions.

· Take Efavir (Efavirenz) by mouth on an empty stomach. Taking Efavir (Efavirenz) with food, especially with a high-fat meal, may lead to increased blood levels of Efavir (Efavirenz). This may increase your risk of side effects.

· Take Efavir (Efavirenz) with a full glass of water (8 oz [240 mL]).

· Swallow Efavir (Efavirenz) whole. Do not break, crush, or chew before swallowing. If you cannot swallow Efavir (Efavirenz) whole, tell your doctor.

· Do NOT take more than the recommended dose, change your dose, or stop taking Efavir (Efavirenz) without checking with your doctor.

· Take Efavir (Efavirenz) at the same time every day, preferably at bedtime unless otherwise directed by your doctor.

· Continue to use Efavir (Efavirenz) even if you feel well. Do not miss any doses.

 

Side effects:

Dizziness, trouble sleeping, drowsiness, unusual dreams, and trouble concentrating may frequently occur. These side effects may begin 1-2 days after starting this medication and usually go away in 2-4 weeks. They are also reduced by taking Efavir (Efavirenz) on an empty stomach at bedtime. Avoid alcohol and street drugs while taking Efavir (Efavirenz). They may worsen these side effects. Tiredness, headache, nausea, vomiting, and diarrhea may also occur.

Precaution:

Before taking Efavir (Efavirenz), tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

 

Store:

Store Efavir (Efavirenz) at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store in a tightly closed container away from heat, moisture, and light.

Duovir (Zidovudine /Lamivudine) Medicines

Approx Price: Rs 1,020 / Bottle 
Minimum Order Quantity: 1 Bottle
Item Code: 85671748

Duovir (Zidovudine /Lamivudine)

Brand name: Duovir

Active Ingeridents(Generic Name) : Zidovudine /Lamivudine

Company Name: Cipla

Package :60 Tablets /Bottle

Strength : Zidovudine 300mg + Lamivudine 150mg

Indication:

Duovir (Zidovudine /Lamivudine) are antiviral medications that prevent human immunodeficiency virus (HIV) cells from multiplying in your body.

Duovir (Zidovudine /Lamivudine) is a combination medicine used to treat HIV, which causes the acquired immunodeficiency syndrome (AIDS). This medicine is not a cure for HIV or AID.

 

 

Mechanism of action:

Zidovudine:

Zidovudine, a structural analog of thymidine, is a prodrug that must be phosphorylated to its active 5′-triphosphate metabolite, zidovudine triphosphate (ZDV-TP). It inhibits the activity of HIV-1 reverse transcriptase (RT) via DNA chain termination after incorporation of the nucleotide analogue. It competes with the natural substrate dGTP and incorporates itself into viral DNA. It is also a weak inhibitor of cellular DNA polymerase α and γ.

Lamivudine:

Lamivudine is a synthetic nucleoside analogue and is phosphorylated intracellularly to its active 5'-triphosphate metabolite, lamivudine triphosphate (L-TP). This nucleoside analogue is incorporated into viral DNA by HIV reverse transcriptase and HBV polymerase, resulting in DNA chain termination.

Dosage and Administration:

Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Duovir (Zidovudine /Lamivudine) can be taken with or without food.

HIV/AIDS is usually treated with a combination of drugs. Use all medications as directed by your doctor. Read the medication guide or patient instructions provided with each medication. Do not change your doses or medication schedule without your doctor's advice. Every person with HIV or AIDS should remain under the care of a doctor.

Side effects:

Headache, tiredness, loss of appetite, nausea, vomiting, diarrhea, trouble sleeping, dizziness, or stuffy nose may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Precaution:

Before taking Duovir (Zidovudine /Lamivudine), tell your doctor or pharmacist if you are allergic to either drug; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney problems, liver problems (such as hepatitis B or C, cirrhosis), disease of the pancreas (pancreatitis), alcohol use, low red/white blood cell counts.

Store: Duovir (Zidovudine /Lamivudine) room temperature away from moisture and heat or cold. Do not freeze.

Daruvir (Darunavir) Medicines

Approx Price: Rs 4,500 / Bottle 
Minimum Order Quantity: 1 Bottle
Item Code: 83994299

Daruvir (Darunavir)

Brand name: Daruvir 

Active Ingeridents(Generic Name) : Darunavir

Company Name: Cipla

Package:60 Tabs/Bottle

Strength : 300mg

Indication:

Treating HIV infection in certain patients along with other antiretroviral medicines. Daruvir (Darunavir) must always be taken along with another medicine called ritonavir. Daruvir (Darunavir) is an HIV protease inhibitor. It works by blocking the growth of HIV.

Mechanism of action:

Daruvir (Darunavir) is a HIV protease inhibitor which prevents HIV replication by binding to the enzyme's active site, thereby preventing the dimerization and the catalytic activity of the HIV-1 protease. Daruvir (Darunavir) selectively inhibits the cleavage of HIV encoded Gag-Pol polyproteins in virus-infected cells, which prevents the formation of mature infectious virus particles. Structual analyses suggests that the close contact that Daruvir (Darunavir) has with the main chains of the protease active site amino acids (Asp-29 and Asp-30) is an important contributing factor to its potency and wide spectrum of activity against multi-protease inhibitor resistant HIV-1 variants. Daruvir (Darunavir) can also adapt to the changing shape of a protease enzyme because of its molecular flexibility. Daruvir (Darunavir) is known to bind to two distinct sites on the enzyme: the active site cavity and the surface of one of the flexible flaps in the protease dimer.

 

Dosage and Administration:

Use Daruvir (Darunavir) as directed by your doctor. Check the label on the medicine for exact dosing instructions.

 

· Take Daruvir (Darunavir) by mouth with food. Ritonavir should be taken at the same time as Daruvir (Darunavir).

· Swallow Daruvir (Darunavir) whole with a drink, such as water or milk. Do not break, crush, or chew before swallowing. If you are unable to swallow Daruvir (Darunavir) whole, contact your doctor. Daruvir (Darunavir) may not be right for you.

· If you also take didanosine, do not take it within 1 hour before or 2 hours after taking Daruvir (Darunavir). Check with your doctor if you have questions.

· Taking Daruvir (Darunavir) at the same time(s) each day will help you remember to take it.

· Continue to take Daruvir (Darunavir) even if you feel well. Do not miss any doses.

 

Side effects:

Since Daruvir (Darunavir) is always taken with other HIV medications, it may be difficult to tell whether Daruvir (Darunavir) is causing certain side effects. However, Daruvir (Darunavir) is known to cause diarrhea, nausea, vomiting, stomach pain, and headache. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Precaution:

Before taking Daruvir (Darunavir), tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. Since Daruvir (Darunavir) must be taken with ritonavir, tell your doctor if you are allergic to ritonavir. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Store:

Store Daruvir (Darunavir) at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light.

Daruvir (Darunavir) Medicines

Approx Price: Rs 10,500 / Bottle 
Minimum Order Quantity: 1 Bottle
Item Code: 83994255

Daruvir (Darunavir)

Brand name: Daruvir 

Active Ingeridents(Generic Name) : Darunavir

Company Name: Cipla

Package:60 Tabs/Bottle

Strength : 600mg

Indication:

Treating HIV infection in certain patients along with other antiretroviral medicines. Daruvir (Darunavir) must always be taken along with another medicine called ritonavir. Daruvir (Darunavir) is an HIV protease inhibitor. It works by blocking the growth of HIV.

Mechanism of action:

Daruvir (Darunavir) is a HIV protease inhibitor which prevents HIV replication by binding to the enzyme's active site, thereby preventing the dimerization and the catalytic activity of the HIV-1 protease. Daruvir (Darunavir) selectively inhibits the cleavage of HIV encoded Gag-Pol polyproteins in virus-infected cells, which prevents the formation of mature infectious virus particles. Structual analyses suggests that the close contact that Daruvir (Darunavir) has with the main chains of the protease active site amino acids (Asp-29 and Asp-30) is an important contributing factor to its potency and wide spectrum of activity against multi-protease inhibitor resistant HIV-1 variants. Daruvir (Darunavir) can also adapt to the changing shape of a protease enzyme because of its molecular flexibility. Daruvir (Darunavir) is known to bind to two distinct sites on the enzyme: the active site cavity and the surface of one of the flexible flaps in the protease dimer.

 

Dosage and Administration:

Use Daruvir (Darunavir) as directed by your doctor. Check the label on the medicine for exact dosing instructions.

· Take Daruvir (Darunavir) by mouth with food. Ritonavir should be taken at the same time as Daruvir (Darunavir).

· Swallow Daruvir (Darunavir) whole with a drink, such as water or milk. Do not break, crush, or chew before swallowing. If you are unable to swallow Daruvir (Darunavir) whole, contact your doctor. Daruvir (Darunavir) may not be right for you.

· If you also take didanosine, do not take it within 1 hour before or 2 hours after taking Daruvir (Darunavir). Check with your doctor if you have questions.

· Taking Daruvir (Darunavir) at the same time(s) each day will help you remember to take it.

· Continue to take Daruvir (Darunavir) even if you feel well. Do not miss any doses.

 

Side effects:

Since Daruvir (Darunavir) is always taken with other HIV medications, it may be difficult to tell whether Daruvir (Darunavir) is causing certain side effects. However, Daruvir (Darunavir) is known to cause diarrhea, nausea, vomiting, stomach pain, and headache. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Precaution:

Before taking Daruvir (Darunavir), tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. Since Daruvir (Darunavir) must be taken with ritonavir, tell your doctor if you are allergic to ritonavir. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Store:

Store Daruvir (Darunavir) at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light.

Atazor-R (Atazanavir / Ritonavir )

Approx Price: Rs 2,800 / Bottle 
Minimum Order Quantity: 1 Bottle
Item Code: 85673776

 

Atazor-R (Atazanavir / Ritonavir )

Brand name: Atazor-R 

Active Ingeridents(Generic Name) : Atazanavir / Ritonavir

Company Name: Emcure

Package : 30 Tablets/Bottle

Strength : Atazanavir 300mg + Ritonavir 100mg

Indication:

Treating HIV infection. It is used along with other medicines for HIV. Atazor-R (Atazanavir / Ritonavir )is a combination of 2 HIV protease inhibitors. It works by stopping the HIV virus from multiplying.

 

 

Mechanism of action:

Atazanavir:

Atazanavir selectively inhibits the virus-specific processing of viral Gag and Gag-Pol polyproteins in HIV-1 infected cells by binding to the active site of HIV-1 protease, thus preventing the formation of mature virions. Atazanavir is not active against HIV-2.

Ritonavir :

Ritonavir inhibits the HIV viral proteinase enzyme which prevents cleavage of the gag-pol polyprotein, resulting in noninfectious, immature viral particles.

 

Dosage and Administration:

· An extra patient leaflet is available with Atazor-R (Atazanavir / Ritonavir ). Talk to your pharmacist if you have questions about this information.

· Take Atazor-R (Atazanavir / Ritonavir )by mouth with or without food.

· Continue to take Atazor-R (Atazanavir / Ritonavir )even if you feel well. Do not miss any doses.

· Taking Atazor-R (Atazanavir / Ritonavir )at the same time each day will help you remember to take it.

· If you miss a dose of Atazor-R (Atazanavir / Ritonavir ), take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Side effects:

Below are the common side effects that may occur when using Atazor-R (Atazanavir / Ritonavir )Tablet. Please consult your doctor if you observe any of these side effects even in mild form.

· Abdominal pain , Accumulation of body fat, Anxiety, Asthma

 

Precaution:

Take the following precautions or be careful about the following while consuming Atazor-R (Atazanavir / Ritonavir ) Tablet:

· Children , Consult a doctor if you have haemophilia or pancreatitis, Kidney problems

 

store: Atazor-R (Atazanavir / Ritonavir )room temperature away from moisture and heat or cold. Do not freeze.

Tenvir EM Tablet

Approx Price: Rs 1,500 / Bottle 
Minimum Order Quantity: 1 Bottle
Uses:
  • Tenvir EM Tablet is used in combination with other antiretroviral medications for the treatment of HIV-1 infection in adults
  • It is also used to treat chronic hepatitis B infection
  • It may also be used for other conditions as determined by your doctor
  • Tenvir–EM is an antiviral reverse transcriptase inhibitor
  • It works to treat HIV infection by reducing the amount of HIV (the virus that causes AIDS) in the body by blocking the ability of the virus to multiply
  • It works to treat HBV infection by reducing the amount of HBV in the body by blocking the ability of the virus to multiply and infect new liver cells
  • Tenvir–EM is not a cure for HIV or AIDS

Terbinafine Tablets

Approx Price: Rs 15 / Box 
Minimum Order Quantity: 1 Box
Item Code: 65369482We have carved a niche in offering a supreme quality Terbinafine Tablets which is an acyclic nucleoside phosphonate diester analog o monophosphate. Offered Tenvir-em tablet is indicated in combination with other antiretroviral agents for the treatment of HIV-1 infection in adults. our provided Tenvir-em tablet is formulated by vendor’s medical experts using quality ingredients in compliance with the standards of medical industry.
Features:
  • Highly effective
  • No side effects
  • Available in various packaging option

Side effects:
  • Headache
  • Nausea
  • Diarrhea

Lamivir HBV (Lamivudine)

Approx Price: Rs 108 / Piece 
Minimum Order Quantity: 1 Piece
Item Code: 83994504

LamivirHBV (Lamivudine)

Brand name: LamivirHBV

Active Ingeridents(Generic Name) : Lamivudine

Company Name: Cipla

Package:10 Tablets

Strength : 100mg

Indication:

This drug is used with other HIV medications to help control HIV infection. It helps to decrease the amount of HIV in your body so your immune system can work better. This lowers your chance of getting HIV complications (such as new infections, cancer) and improves your quality of life. LamivirHBV (Lamivudine) belongs to a class of drugs known as nucleoside reverse transcriptase inhibitors-NRTI.

Mechanism of action:

LamivirHBV (Lamivudine) is an analogue of cytidine. It can inhibit both types of HIV reverse transcriptase and also the reverse transcriptase of hepatitis B virus. It is phosphorylated to active metabolites that compete for incorporation into viral DNA. They inhibit the HIV reverse transcriptase enzyme competitively and act as a chain terminator of DNA synthesis. The lack of a 3'-OH group in the incorporated nucleoside analogue prevents the formation of the 5' to 3' phosphodiester linkage essential for DNA chain elongation, and therefore, the viral DNA growth is terminated.

LamivirHBV (Lamivudine) is administered orally, and it is rapidly absorbed with a bio-availability of over 80%. Some research suggests that LamivirHBV (Lamivudine) can cross the blood–brain barrier. LamivirHBV (Lamivudine) is often given in combination with zidovudine, with which it is highly synergistic. LamivirHBV (Lamivudine) treatment has been shown to restore zidovudine sensitivity of previously resistant HIV. LamivirHBV (Lamivudine) showed no evidence of carcinogenicity or mutagenicity in in vivo studies in mice and rats at doses from 10 to 58 times those used in humans.

Dosage and Administration:

Use LamivirHBV (Lamivudine) as directed by your doctor. Check the label on the medicine for exact dosing instructions.

· Take LamivirHBV (Lamivudine) by mouth with or without food.

· Continue to take LamivirHBV (Lamivudine) even if you feel well. Do not miss any doses.

· Taking LamivirHBV (Lamivudine) at the same time each day will help you remember to take it.

· If you miss a dose of LamivirHBV (Lamivudine), take it as soon as possible. If it is within 2 hours of your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Side effects:

See also Warning section.

Headache, dizziness, nausea, diarrhea, or trouble sleeping may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.

Precaution:

Before taking LamivirHBV (Lamivudine), tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: pancreatitis, kidney problems, liver problems (such as hepatitis B or C, cirrhosis), alcohol use.

Store:

Store LamivirHBV (Lamivudine) at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light.

Tenvir EM Tablet

Approx Price: Rs 1,500 / Pack 
Minimum Order Quantity: 1 Pack
Uses:
  • Tenvir EM Tablet is used in combination with other antiretroviral medications for the treatment of HIV-1 infection in adults
  • It is also used to treat chronic hepatitis B infection
  • It may also be used for other conditions as determined by your doctor
  • Tenvir–EM is an antiviral reverse transcriptase inhibitor
  • It works to treat HIV infection by reducing the amount of HIV (the virus that causes AIDS) in the body by blocking the ability of the virus to multiply
  • It works to treat HBV infection by reducing the amount of HBV in the body by blocking the ability of the virus to multiply and infect new liver cells
  • Tenvir–EM is not a cure for HIV or AIDS.

Daruvir (Darunavir) Medicines

Approx Price: Rs 10,500 / Bottle 
Minimum Order Quantity: 1 Bottle
Indication:
  • Treating HIV infection in certain patients along with other antiretroviral medicines.
  • Daruvir (Darunavir) must always be taken along with another medicine called ritonavir.
  • Daruvir (Darunavir) is an HIV protease inhibitor.
  • It works by blocking the growth of HIV.


Mechanism of action:

  • Daruvir (Darunavir) is a HIV protease inhibitor which prevents HIV replication by binding to the enzyme's active site, thereby preventing the dimerization and the catalytic activity of the HIV-1 protease.
  • Daruvir (Darunavir) selectively inhibits the cleavage of HIV encoded Gag-Pol polyproteins in virus-infected cells, which prevents the formation of mature infectious virus particles. Structual analyses suggests that the close contact that Daruvir (Darunavir) has with the main chains of the protease active site amino acids (Asp-29 and Asp-30) is an important contributing factor to its potency and wide spectrum of activity against multi-protease inhibitor resistant HIV-1 variants. Daruvir (Darunavir) can also adapt to the changing shape of a protease enzyme because of its molecular flexibility.
  • Daruvir (Darunavir) is known to bind to two distinct sites on the enzyme: the active site cavity and the surface of one of the flexible flaps in the protease dimer.
 

Side effects:

  • Since Daruvir (Darunavir) is always taken with other HIV medications, it may be difficult to tell whether Daruvir (Darunavir) is causing certain side effects.
  • However, Daruvir (Darunavir) is known to cause diarrhea, nausea, vomiting, stomach pain, and headache.
  • If any of these effects persist or worsen, tell your doctor or pharmacist promptly.


Precaution:

  • Before taking Daruvir (Darunavir), tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies.
  • Since Daruvir (Darunavir) must be taken with ritonavir, tell your doctor if you are allergic to ritonavir.
  • This product may contain inactive ingredients, which can cause allergic reactions or other problems.
  • Talk to your pharmacist for more details.


Store:

  • Store Daruvir (Darunavir) at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted.
  • Store away from heat, moisture, and light.

Tenvir (Tenofovir ) Medicines

Approx Price: Rs 1,500 / Bottle 
Minimum Order Quantity: 1 Bottle

Tenvir (Tenofovir )

Brand name: Tenvir

Active Ingeridents(Generic Name) : Tenofovir disoproxil Fumerate

Company Name: Cipla

Package:30 Tablets

Strength : 300mg

Indication:

Tenvir (Tenofovir ) is used with other HIV medications to help control HIV infection. It helps to decrease the amount of HIV in your body so your immune system can work better. This lowers your chance of getting HIV complications (such as new infections, cancer) and improves your quality of life.

Mechanism of action:

Tenvir (Tenofovir ) is a defective adenosine nucleotide that selectively inhibits the action of reverse transcriptase, while only weakly interfering with mammalian DNA polymerases α, β, and mitochondrial DNA polymerase γ. Tenvir (Tenofovir ) prevents the formation of the 5′ to 3′ phosphodiester linkage essential for DNA chain elongation. A phosphodiester bond cannot be formed because the Tenvir (Tenofovir ) molecule lacks an —OH group on the 3′ carbon of its deoxyribose sugar. Once incorporated into a growing DNA strand, Tenvir (Tenofovir ) causes premature termination of DNA transcription. The drug is classified as a nucleotide analogue reverse transcriptase inhibitor (NtRTI). Reverse transcriptase is a crucial viral enzyme in retroviruses such as human immunodeficiency virus (HIV) and in hepatitis B virus infections.

Dosage and Administration:

Use Tenvir (Tenofovir ) as directed by your doctor. Check the label on the medicine for exact dosing instructions.

 

· An extra patient leaflet is available with Tenvir (Tenofovir ). Talk to your pharmacist if you have questions about this information.

· Take Tenvir (Tenofovir ) by mouth with or without food.

· Continue to take Tenvir (Tenofovir ) even if you feel well. Do not miss any doses.

· Taking Tenvir (Tenofovir ) at the same time each day will help you remember to take it.

· Do not suddenly stop taking Tenvir (Tenofovir ) without checking with your doctor. This may cause the virus to become less sensitive to this or other medicines. If you have hepatitis B, your condition could become worse if you suddenly stop taking Tenvir (Tenofovir ).

· If you miss a dose of Tenvir (Tenofovir ), take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Side effects:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Back pain; diarrhea; dizziness; gas; headache; indigestion; loss of appetite; nausea; runny or stuffy nose; sweating; tiredness; trouble sleeping; vomiting; weakness; weight loss.

Precaution:

Before taking Tenvir (Tenofovir ), tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

 

Store: Store Tenvir (Tenofovir ) at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light.

Tenofovir Tablet

Approx Price: Rs 1,500 / Bottle 
Minimum Order Quantity: 1 Bottle
Tenvir is an antiviral reverse transcriptase inhibitor. It works to treat HIV infection by reducing the amount of HIV (the virus that causes AIDS) in the body by blocking the ability of the virus to multiply. Each film coated tablet of Tenvir contains 300 mg of Tenofovir disoproxil fumarate which is equivalent to 245 mg of Tenofovir disoproxil. Tenofovir Disoproxil Fumarate Tablets is used for Treating HIV infection in combination with other medicines. It is also used to treat chronic hepatitis B infection. It may also be used for other conditions as determined by your doctor. Tenvir is an antiviral reverse transcriptase inhibitor. Tenofovir Disoproxil Fumarate works to treat HIV infection by reducing the amount of HIV (the virus that causes AIDS) in the body by blocking the ability of the virus to multiply. Tenofovir works to treat HBV infection by reducing the amount of HBV in the body by blocking the ability of the virus to multiply and infect new liver cells. Tenvir is not a cure for HIV or AIDS. Use Tenvir as directed by your doctor. Check the label on the medicine for exact dosing instructions.An extra patient leaflet is available with Tenvir . Talk to your pharmacist if you have questions about this information.Take Tenvir tablets by mouth with or without food.Continue to take Tenvir even if you feel well. Do not miss any doses.Taking Tenvir at the same time each day will help you remember to take it.Do not suddenly stop taking Tenvir Tablets without checking with your doctor. This may cause thevirus to become less sensitive to this or other medicines. Also, some conditions (eg, hepatitis B) could become worse if you suddenly stop taking Tenofovir Disoproxil Fumarate Tablets (Tenvir) .If you miss a dose of Tenvir, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once. Ask your health care provider any questions you may have about how to use

Ritomune (Ritonavir) Medicines

Approx Price: Rs 1,800 / Bottle 
Minimum Order Quantity: 1 Bottle
Indication:
  • Ritomune (Ritonavir) is an antiretroviral medication used along with other medications to treat HIV/AIDS This combination treatment is known as highly active antiretroviral therapy.
  • Often a low dose is used with other protease inhibitors. It may also be used in combination with other medications for hepatitis C.


Mechanism of action:

  • Ritomune (Ritonavir) was originally developed as an inhibitor of HIV protease. It is one of the most complex inhibitors.
  • It is now rarely used for its own antiviral activity, but remains widely used as a booster of other protease inhibitors.
  • More specifically, Ritomune (Ritonavir) is used to inhibit a particular liver enzyme that normally metabolizes protease inhibitors, cytochrome P450-3A4 (CYP3A4).
  • The drug's molecular structure inhibits CYP3A4, so a low dose can be used to enhance other protease inhibitors.
  • This discovery, which has drastically reduced the adverse effects and improved the efficacy of protease inhibitors and HAART, was first communicated in an article published in the journal AIDS in 1997 by researchers at the University of Liverpool.
  • This effect does come with a price: it also affects the efficacy of numerous other medications, making it difficult to know how to administer them concurrently.

Precaution:

  • Before taking Ritomune (Ritonavir), tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
  • Before using this medication, tell your doctor or pharmacist your medical history, especially of: diabetes, heart problems (coronary artery disease, heart attack), hemophilia, high cholesterol/triglycerides, gout/high uric acid in the blood, liver problems (such as hepatitis B, hepatitis C), pancreatitis

 

Store:

  • Store Ritomune (Ritonavir) in the original container at room temperature up to 86 degrees F (30 degrees C).
  • If stored outside of the original container, throw away any part not used after 2 weeks.
  • Storage at temperatures up to 122 degrees F (50 degrees C) is permitted for up to 7 days.
  • Store away from heat, moisture, and light.

Nevimune (Nevirapine)

Approx Price: Rs 850 / Bottle 
Minimum Order Quantity: 1 Bottle

Nevimune (Nevirapine)

Brand name: Nevimune

Active Ingeridents(Generic Name) : Nevirapine

Company Name: Cipla

Package:60 Tablets/Bottle

Strength : 200mg

Indication:

This drug is used with other HIV medications to help control HIV infection. It helps to decrease the amount of HIV in your body so your immune system can work better. This lowers your chance of getting HIV complications (such as new infections, cancer) and improves your quality of life. Nevimune (Nevirapine) belongs to a class of drugs known as non-nucleoside reverse transcriptase inhibitors (NNRTIs).

Mechanism of action:

Nevimune (Nevirapine) falls in the non-nucleoside reverse transcriptase inhibitor (NNRTI) class of antiretrovirals. Both nucleoside and non-nucleoside RTIs inhibit the same target, the reverse transcriptase enzyme, an essential viral enzyme which transcribes viral RNA into DNA. Unlike nucleoside RTIs, which bind at the enzyme's active site, NNRTIs bind allosterically at a distinct site away from the active site termed the NNRTI pocket.

Nevimune (Nevirapine) is not effective against HIV-2, as the pocket of the HIV-2 reverse transcriptase has a different structure, which confers intrinsic resistance to the NNRTI class.

Resistance to Nevimune (Nevirapine) develops rapidly if viral replication is not completely suppressed. The most common mutations observed after Nevimune (Nevirapine) treatment are Y181C and K103N, which are also observed with other NNRTIs. As all NNRTIs bind within the same pocket, viral strains which are resistant to Nevimune (Nevirapine) are usually also resistant to the other NNRTIs, efavirenz and delavirdine. However, second generation NNRTIs like rilpivirine and etravirine are effective in treatment for HIV strains resistant to Nevimune (Nevirapine) and other first generation drugs in that same class.

Dosage and Administration:

Use Nevimune (Nevirapine) as directed by your doctor. Check the label on the medicine for exact dosing instructions.

· Nevimune (Nevirapine) comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get Nevimune (Nevirapine) refilled.

· Take Nevimune (Nevirapine) by mouth with or without food.

· Taking Nevimune (Nevirapine) at the same time each day will help you remember to take it.

· Continue to take Nevimune (Nevirapine) even if you feel well. Do not miss any doses.

Side effects:

Tiredness, nausea, vomiting, or diarrhea may occur. Drowsiness may rarely occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Precaution:

Before taking Nevimune (Nevirapine), tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver problems (such as hepatitis B or C, cirrhosis), kidney dialysis, lactose or galactose intolerance.

Store:

Store Nevimune (Nevirapine) at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store in a tightly closed container. Store away from heat, moisture, and light.

Valten (Tenofovir) Medicines

Approx Price: Rs 2,000 / Piece 
Minimum Order Quantity: 1 Piece
Indication:
  • Valten (Tenofovir )is used with other HIV medications to help control HIV infection.
  • It helps to decrease the amount of HIV in your body so your immune system can work better.
  • This lowers your chance of getting HIV complications (such as new infections, cancer) and improves your quality of life.

 

Mechanism of action:

  • Valten (Tenofovir )is a defective adenosine nucleotide that selectively inhibits the action of reverse transcriptase, while only weakly interfering with mammalian DNA polymerases α, β, and mitochondrial DNA polymerase γ.
  • Valten (Tenofovir )prevents the formation of the 5′ to 3′ phosphodiester linkage essential for DNA chain elongation.
  • A phosphodiester bond cannot be formed because the Valten (Tenofovir )molecule lacks an —OH group on the 3′ carbon of its deoxyribose sugar.
  • Once incorporated into a growing DNA strand, Valten (Tenofovir )causes premature termination of DNA transcription.
  • The drug is classified as a nucleotide analogue reverse transcriptase inhibitor (NtRTI).
  • Reverse transcriptase is a crucial viral enzyme in retroviruses such as human immunodeficiency virus (HIV) and in hepatitis B virus infections.

Daruvir 300mg

Approx Price: Rs 4,500 / Pack 
Minimum Order Quantity: 1 Pack
Specifications:

  • Drug name: Darunavir
  • Strength: 600 Mg
  • Packing : Pack of 60 Tablet

 

Uses :

 

  • This medication is an antiviral agent, prescribed for HIV infection with other antiviral agents
  • It is a protease inhibitor and blocks the enzyme activity
  • This medication slows down the spread of virus in the body

Naivex

Approx Price: Rs 2,300 / Bottle 
Minimum Order Quantity: 1 Bottle

(DTG) is an FDA-approved drug for the treatment of HIV infection. Dolutegravir is an integrase inhibitor. Mechanism of action:Naivex (Dolutegravir)is an HIV-1 antiviral agent. It inhibits HIV integrase by binding to the active site and blocking the strand transfer step to retroviral DNA integration. This is an essential step of the HIV replication cycle and will result in an inhibition of viral activity. Naivex (Dolutegravir)has a mean EC50 value of 0.5 nM (0.21 ng/mL) to 2.1 nM (0.85 ng/mL) in peripheral blood mononuclear cells (PBMCs) and MT-4 cells.Dosage and Administration:Use Naivex (Dolutegravir)as directed by your doctor. Check the label on the medicine for exact dosing instructions.

A-Bec (Abacavir)

Approx Price: Rs 1,500 / Bottle 
Minimum Order Quantity: 1 Bottle
Indication:
  • This drug is used with other HIV medications to help control HIV infection.
  • It helps to decrease the amount of HIV in your body so your immune system can work better.
  • This lowers your chance of getting HIV complications (such as new infections, cancer) and improves your quality of life. A-Bec (Abacavir) belongs to a class of drugs known as nucleoside reverse transcriptase inhibitors-NRTI.


Mechanism of action:

  • A-Bec (Abacavir) is a carbocyclic synthetic nucleoside analogue and an antiviral agent.
  • Intracellularly, A-Bec (Abacavir) is converted by cellular enzymes to the active metabolite carbovir triphosphate, an analogue of deoxyguanosine-5'-triphosphate (dGTP).
  • Carbovir triphosphate inhibits the activity of HIV-1 reverse transcriptase (RT) both by competing with the natural substrate dGTP and by its incorporation into viral DNA.
  • Viral DNA growth is terminated because the incorporated nucleotide lacks a 3'-OH group, which is needed to form the 5′ to 3′ phosphodiester linkage essential for DNA chain elongation.

Side effects:

  • All medicines may cause side effects, but many people have no, or minor, side effects.
  • Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Warning:

  • A-Bec (Abacavir) is a prescription drug and should be used under proper medical guidance and advice.
  • The information provided here is for general educational purposes only and does not constitute medical or pharmaceutical advice which should be sought from qualified medical and pharmaceutical advisers.

Efamat 600 Mg Tablet

Approx Price: Rs 1,893 / Bottle 
Minimum Order Quantity: 1 Bottle
Efamat 600 mg tablet belongs to a class of antiretroviral medications called non-nucleoside reverse transcriptase inhibitors (NNRTIs). It inhibits the replication of HIV, thereby reducing the amount of the virus in the blood. Common side effects Depression, Nightmare, Impaired concentration, Indigestion, Insomnia, Vomiting, Diarrhoea, Headache, Nervousness, Abdominal pain, Rash, Suicidal thoughts, Dizziness, Stomach upset, Confusion, Memory loss.

Efferven 600 (MG) Tablet

Approx Price: Rs 2,382 / Bottle 
Minimum Order Quantity: 1 Bottle
Efferven 600mg tablet belongs to a class of antiretroviral medications called non-nucleoside reverse transcriptase inhibitors (NNRTIs). It inhibits the replication of HIV, thereby reducing the amount of the virus in the blood. Common side effects Depression, Nightmare, Impaired concentration, Indigestion, Insomnia, Vomiting, Diarrhoea, Headache, Nervousness, Abdominal pain, Rash, Suicidal thoughts, Dizziness, Stomach upset, Confusion, Memory loss.

Efcure Tablet

Approx Price: Rs 2,382 / Bottle 
Minimum Order Quantity: 1 Bottle
Efcure 600mg tablet belongs to a class of antiretroviral medications called non-nucleoside reverse transcriptase inhibitors (NNRTIs). It inhibits the replication of HIV, thereby reducing the amount of the virus in the blood. Common side effects Depression, Nightmare, Impaired concentration, Indigestion, Insomnia, Vomiting, Diarrhoea, Headache, Nervousness, Abdominal pain, Rash, Suicidal thoughts, Dizziness, Stomach upset, Confusion, Memory loss.

Erlocip (Erlotinib)

Approx Price: Rs 6,660 / Bottle 
Minimum Order Quantity: 1 Bottle
Indication:
  • It is used to treat non-small cell lung cancer (NSCLC), pancreatic cancer and several other types of cancer.
  • It is a reversible tyrosine kinase inhibitor, which acts on the epidermal growth factor receptor (EGFR). 

 

Mechanism of action:

  • Erlotinib is an epidermal growth factor receptor inhibitor (EGFR inhibitor).
  • The drug follows Iressa (gefitinib), which was the first drug of this type.
  • Erlotinib specifically targets the epidermal growth factor receptor (EGFR) tyrosine kinase, which is highly expressed and occasionally mutated in various forms of cancer.
  • It binds in a reversible fashion to the adenosine triphosphate (ATP) binding site of the receptor.
  • For the signal to be transmitted, two EGFR molecules need to come together to form a homodimer.
  • These then use the molecule of ATP to trans-phosphorylate each other on tyrosine residues, which generates phosphotyrosine residues, recruiting the phosphotyrosine-binding proteins to EGFR to assemble protein complexes that transduce signal cascades to the nucleus or activate other cellular biochemical processes.
  • When erlotinib binds to EGFR, formation of phosphotyrosine residues in EGFR is not possible and the signal cascades are not initiated. 

 

Precaution:
  • Before starting erlotinib treatment, make sure you tell your doctor about any other medications you are taking (including prescription, over-the-counter, vitamins, herbal remedies, etc.).
  • Certain medications can interfere with the levels/effects of erlotinib.
  • It is important your oncologist is aware of all medications. Do not take aspirin, or products containing aspirin unless your doctor specifically permits this.

 


Store:

  • Erlotinibroom temperature away from moisture and heat.

Naivex

Approx Price: Rs 2,500 / Bottle 
Minimum Order Quantity: 1 Bottle

(DTG) is an FDA-approved drug for the treatment of HIV infection. Dolutegravir is an integrase inhibitor. Mechanism of action:NAIVEX (Dolutegravir)is an HIV-1 antiviral agent. It inhibits HIV integrase by binding to the active site and blocking the strand transfer step to retroviral DNA integration. This is an essential step of the HIV replication cycle and will result in an inhibition of viral activity. NAIVEX (Dolutegravir)has a mean EC50 value of 0.5 nM (0.21 ng/mL) to 2.1 nM (0.85 ng/mL) in peripheral blood mononuclear cells (PBMCs) and MT-4 cells.Dosage and Administration:Use Naivex (Dolutegravir)as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Naivex

Approx Price: Rs 2,250 / Bottle 
Minimum Order Quantity: 1 Bottle

What is Dolutegravir: Dolutegravir (DTG) is an FDA-approved drug. it is used for the treatment and the management of HIV infection. Dolutegravir is an integrase inhibitor.By blocking integrase, integrase inhibitors prevent HIV from multiplying and can reduce the amount of HIV in the body.

Velasof

Approx Price: Rs 13,990 / Bottle 
Minimum Order Quantity: 1 Bottle
Indication:
  • Velasof is an combination of velpatasvir 100mg+ Sofosbuvir 400mg.
  • Velasof is a two-drug combination for the treatment of hepatitis C.
  • It is administered as a single daily pill containing the viral NS5A inhibitor velpatasvir and sofosbuvir,a nucleotide inhibitor of the viral RNA polymerase.
  • It is the first treatment, that works for all genotypic, and is taken entirely by mouth.
  • A single tablet regimen is used for adults with genotype 1-6 chronic hepatitis C virus (HCV) infection with pangenotypic activity.

Side effects:

  • The most common adverse reactions with velpatasvir were headache and fatigue and when used with RBV in decompensated cirrhotics were fatigue, anemia, nausea, headache, insomnia, and diarrhea.
  • Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects.
  • Many people using this medication do not have serious side effects.


 

Naivex

Approx Price: Rs 2,400 / Bottle 
Minimum Order Quantity: 1 Bottle

(DTG) is an FDA-approved drug for the treatment of HIV infection. Dolutegravir is an integrase inhibitor. Mechanism of action:NAIVEX (Dolutegravir)is an HIV-1 antiviral agent. It inhibits HIV integrase by binding to the active site and blocking the strand transfer step to retroviral DNA integration. This is an essential step of the HIV replication cycle and will result in an inhibition of viral activity. NAIVEX (Dolutegravir)has a mean EC50 value of 0.5 nM (0.21 ng/mL) to 2.1 nM (0.85 ng/mL) in peripheral blood mononuclear cells (PBMCs) and MT-4 cells.Dosage and Administration:Use Naivex (Dolutegravir)as directed by your doctor. Check the label on the medicine for exact dosing instructions.

 

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